About :: Principal Investigators

Dr. Charles Craik Investigator

An emphasis of our work is on identifying the roles and regulating the activity of proteases associated with infectious diseases, cancer and development. The research efforts of the lab focus primarily on the structure-function analysis of proteases and their inhibitors using a combination of genetic, biochemical and biophysical methods. These studies are providing a better understanding of both the chemical make-up and the biological importance of these critical proteins. This in turn is leading to the development of strategies for regulating proteolytic activity as a means of therapeutic intervention. Further study of these proteins holds promise for better understanding, rapid detection and eventual control of infectious diseases and cancer.

Email : craik at cgl.ucsf.edu
Website : http://www.craiklab.ucsf.edu/